Webster's English Dictionary

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quire

1. quire \'kwi-(*)r\ n [ME quair four sheets of paper folded once, 
   collection of sheets, fr. MF]quaer, fr. (assumed) VL quadernum, alter. of L 
   quaterni four each, set of four - more at QUATERNION : a collection of 24 
   or sometimes 25 sheets of paper of the same size and  quality : 1/20 ream
2. quire  var of CHOIR