virulent
vir.u.lent \-l*nt\ aj [ME, fr. L virulentus, fr. virus poison] 1a: marked by a rapid, severe and malignant course {a ~ infection)> 1b: able to overcome bodily defensive mechanisms {a ~ pathogen} 2: extremely poisonous or venomous : NOXIOUS 3: full of malice : MALIGNANT 4: objectionably harsh or strong - vir.u.lent.ly av