Webster's English Dictionary

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tweak

1. tweak \'twe-k\ vb [ME twikken, fr. OE twiccian to pluck - more at 
   TWITCH] 1: to pinch and pull with a sudden jerk and twist : TWITCH  2: to 
   pinch the nose of {~ a baby}  : TWITCH 
2. tweak n 1: an act of tweaking : PINCH  2: AGITATION, DISTRESS