Webster's English Dictionary

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antagonism

Cross references:
  1. enmity                
 
an.tag.o.nism \an-'tag-*-.niz-*m\ n 1a: actively expressed opposition, 
   hostility, or antipathy  1b: opposition or contrariety of a conflicting 
   force, tendency, or principle 2: opposition in physiological action; esp : 
   interaction of two or  more substances such that the action of any one of 
   them on living cells or tissues is modified