Webster's English Dictionary

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manipulate

Cross references:
  1. handle                
 
ma.nip.u.late \m*-'nip-y*-.la-t\ \-.la-t-iv\ \-.la-t-*r\ \-l*-.to-r-e-, 
   -.to.r-\ vt [back-formation fr. manipulation] 1: to treat or operate with 
   the hands or by mechanical means esp. with ski ll 2a: to manage or utilize 
   skillfully  2b: to control or play upon by artful, unfair, or insidious 
   means esp. to  one's own advantage 3: to change by artful or unfair means 
   so as to serve one's purpose : MDOCTOR - ma.nip.u.la.tive aj