Webster's English Dictionary

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misfortune

mis.for.tune \(')mis-'fo.r-ch*n\ n 1: bad fortune : ADVERSITY  2: an 
   instance of bad luck : MISHAPM may both reger to an incident or conjunction 
   of events that involves a change of fortune, but MISFORTUNE emphasizes the 
   resulting mental or physical distress, MISCHANCE the practical 
   inconvenience or disruption of plans; ADVERSITY cannot refer to an 
   instance; it implies serious and continued misfortune SYN syn MISCHANCE, 
   ADVERSITY: MISFORTUNE and MISCHANCE)